Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Key Elements for Plant Nutrition02:35

Key Elements for Plant Nutrition

23.8K
Like all living organisms, plants require organic and inorganic nutrients to survive, reproduce, grow and maintain homeostasis. To identify nutrients that are essential for plant functioning, researchers have leveraged a technique called hydroponics. In hydroponic culture systems, plants are grown—without soil—in water-based solutions containing nutrients. At least 17 nutrients have been identified as essential elements required by plants. Plants acquire these elements from the...
23.8K
Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

636
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
636
Bioavailability Study Design: Healthy Subjects Versus Patients01:15

Bioavailability Study Design: Healthy Subjects Versus Patients

119
Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
119
Proteins: Dietary Sources and Requirements01:28

Proteins: Dietary Sources and Requirements

1.3K
Consuming animal-based products offers high-quality proteins that contain optimal levels and combinations of essential amino acids, crucial for tissue repair and growth. Foods like eggs, milk, fish, and most meats are a source of complete proteins. Legumes and cereals are abundant in proteins; however, they typically lack a full range of essential amino acids. As a result, they are considered incomplete protein sources. Some plant sources like soybeans, quinoa, and amaranth do contain complete...
1.3K
Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

665
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
665
Bioavailability Study Design: Absolute Versus Relative Bioavailability01:27

Bioavailability Study Design: Absolute Versus Relative Bioavailability

252
Bioavailability is a crucial pharmacokinetic parameter that quantifies the proportion of an administered drug that reaches the systemic circulation and is available for therapeutic action. Regulatory agencies mandate the assessment of bioavailability, typically measured as the area under the drug plasma concentration-versus-time curve (AUC), to ensure the efficacy and safety of pharmaceutical products. These evaluations are categorized as absolute and relative bioavailability studies.Absolute...
252

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Human-milk vitamin B-3 (niacin and vitamer) concentrations: secondary analysis of a randomized, placebo-controlled trial of maternal nicotinamide supplementation in rural Tanzania.

The American journal of clinical nutrition·2026
Same author

Stool microbial composition is associated with recent and future diarrhea and fever events in breastfed Danish infants.

mSystems·2026
Same author

Longitudinal association between human milk macronutrient intake and infant growth throughout the first 8.5 months of life: a multicenter cohort study.

The American journal of clinical nutrition·2026
Same author

Intestinal parasitic infections are related to micronutrient status and body composition in Mexican school-age children: results from a cross-sectional study.

Journal of parasitic diseases : official organ of the Indian Society for Parasitology·2026
Same author

Associations between postpartum depressive symptom trajectories and breastfeeding patterns: Results from the MILQ-Brazil study.

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)·2026
Same author

Evaluating the Effect of Random Multi-Donor Pooling on the Nutritional Variability in Donor Human Milk Using Computer Modeling.

Maternal & child nutrition·2026
Same journal

Developing sodium reduction strategy: context-specific frameworks targeting main dietary sources.

Advances in nutrition (Bethesda, Md.)·2026
Same journal

Anthocyanins.

Advances in nutrition (Bethesda, Md.)·2026
Same journal

The Appearance of Validity in Nutrition Science: Why Weak Inferences Persist.

Advances in nutrition (Bethesda, Md.)·2026
Same journal

Immunonutrition Decreases Postoperative Complications in Gastrointestinal Cancer - A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Advances in nutrition (Bethesda, Md.)·2026
Same journal

Human clinical trials of probiotics: a call to improve study design, conduct, and reporting.

Advances in nutrition (Bethesda, Md.)·2026
Same journal

Stunting reversal versus regression to the mean in epidemiological studies of child linear growth in low- and middle-income countries.

Advances in nutrition (Bethesda, Md.)·2026
See all related articles

Related Experiment Video

Updated: Jan 4, 2026

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management
05:35

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management

Published on: January 19, 2024

1.3K

Perspective: Proposed Harmonized Nutrient Reference Values for Populations.

Lindsay H Allen1, Alicia L Carriquiry2, Suzanne P Murphy3

  • 1USDA, Agricultural Research Service, Western Human Nutrition Research Center, Davis, CA, USA.

Advances in Nutrition (Bethesda, Md.)
|November 9, 2019
PubMed
Summary
This summary is machine-generated.

This study proposes harmonized nutrient intake reference values (NRVs), including average requirements (ARs) and tolerable upper intake levels (ULs), for global population assessments. These harmonized values aim to standardize nutrient intake evaluations across diverse regions.

Keywords:
harmonized average requirementharmonized upper levelnutrient intake recommendationsnutrient reference valuenutrient requirement

More Related Videos

'Boden Food Plate': Novel Interactive Web-based Method for the Assessment of Dietary Intake
04:46

'Boden Food Plate': Novel Interactive Web-based Method for the Assessment of Dietary Intake

Published on: September 18, 2018

7.7K
Hydroponics: A Versatile System to Study Nutrient Allocation and Plant Responses to Nutrient Availability and Exposure to Toxic Elements
09:13

Hydroponics: A Versatile System to Study Nutrient Allocation and Plant Responses to Nutrient Availability and Exposure to Toxic Elements

Published on: July 13, 2016

32.6K

Related Experiment Videos

Last Updated: Jan 4, 2026

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management
05:35

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management

Published on: January 19, 2024

1.3K
'Boden Food Plate': Novel Interactive Web-based Method for the Assessment of Dietary Intake
04:46

'Boden Food Plate': Novel Interactive Web-based Method for the Assessment of Dietary Intake

Published on: September 18, 2018

7.7K
Hydroponics: A Versatile System to Study Nutrient Allocation and Plant Responses to Nutrient Availability and Exposure to Toxic Elements
09:13

Hydroponics: A Versatile System to Study Nutrient Allocation and Plant Responses to Nutrient Availability and Exposure to Toxic Elements

Published on: July 13, 2016

32.6K

Area of Science:

  • Nutrition Science
  • Public Health
  • Dietary Assessment

Background:

  • Nutrient intake reference values (NRVs), such as average requirements (ARs) and tolerable upper intake levels (ULs), are crucial for evaluating population nutrient adequacy and safety.
  • Current methodologies for deriving NRVs lack global uniformity, hindering consistent nutrient intake assessments and limiting the availability of essential data.
  • This inconsistency impacts various applications, including public health advice, food fortification strategies, and product labeling.

Purpose of the Study:

  • To present a harmonized approach for deriving global nutrient intake reference values, termed harmonized ARs (H-ARs) and harmonized ULs (H-ULs).
  • To establish a standardized framework for assessing nutrient intakes across diverse populations worldwide.
  • To provide a foundation for consistent global and regional nutrient intake evaluations.

Main Methods:

  • Review and integration of established frameworks and terminology from international bodies like the United Nations University, NASEM, IOM, and EFSA.
  • Selection of harmonized values primarily from the most recent standards set by EFSA (Europe) and IOM (North America).
  • Development of a systematic approach to adapt and combine existing NRVs into globally applicable H-ARs and H-ULs.

Main Results:

  • A proposed methodology for harmonizing NRVs (H-ARs and H-ULs) applicable on a global scale.
  • Identification of specific harmonized values derived from leading international standards (EFSA and IOM).
  • Presentation of justifications and limitations for the proposed harmonized values.

Conclusions:

  • The developed H-ARs and H-ULs offer a feasible solution for consistent global nutrient intake assessment.
  • These harmonized values can be utilized for various applications, including public health initiatives and regulatory guidance.
  • Further international expert review is recommended to refine and validate the proposed harmonized nutrient intake reference values.