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Updated: Jan 4, 2026
A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells
Published on: November 12, 2019
Emerging CAR T cell therapies: clinical landscape and patent technological routes
Virgínia Picanco-Castro1, Cristiano Gonçalves Pereira2, Kamilla Swiech1,3
1Center for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo , Ribeirão Preto, São Paulo, Brazil.
Abstract:
The purpose of this study is to mine CAR-T patents and therapies under development, to design a landscape of the sector and to understand key therapy segments and their current trends. The study analyzed the entire market, consisting of 1624 patent families and 509 biologics under development, to depict an overview of the CAR-T therapies and their state of the art. Our results showed cutting-edge inventions, the major players, the dynamics of cooperation among institutions, the progress of the therapies' generation over the years and future innovation pathways. CAR-T therapies are transforming the current scenario for cancer treatment, and this study reveals the picture of what we can likely expect ahead in order to assist scientists at the academy and industry to improve their research strategies.
Insights
This study maps the CAR-T therapy landscape by analyzing patents and ongoing developments. It reveals key trends and future innovation pathways in CAR-T cancer treatments.
Area of Science:
- Biotechnology
- Oncology
- Intellectual Property Analysis
Background:
- Chimeric Antigen Receptor T-cell (CAR-T) therapies represent a significant advancement in cancer treatment.
- Understanding the evolving landscape of CAR-T therapies is crucial for strategic research and development.
Purpose of the Study:
- To analyze the current state of CAR-T therapies by examining patents and biologics in development.
- To map the CAR-T sector, identify key segments, and understand emerging trends.
- To provide insights into future innovation pathways for CAR-T research.
Main Methods:
- Comprehensive mining of CAR-T patent families (1624 analyzed).
- Analysis of biologics under development (509 identified).
- Landscape mapping of the CAR-T sector and trend identification.
Main Results:
- Identification of cutting-edge inventions and major players in the CAR-T field.
- Analysis of institutional cooperation dynamics and therapy generation progress.
- Mapping of future innovation pathways and current trends in CAR-T development.
Conclusions:
- CAR-T therapies are revolutionizing cancer treatment paradigms.
- This landscape analysis aids academic and industry scientists in refining research strategies.
- Insights into future CAR-T innovations are provided to guide development.
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