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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV
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Dermatology-Driven Quality Improvement Interventions to Decrease Diagnostic Delays for Kaposi Sarcoma in Botswana.

Victoria L Williams1,2,3,4, Mohan Narasimhamurthy1, Olaf Rodriguez4

  • 1University of Botswana, Gaborone, Botswana.

Journal of Global Oncology
|November 9, 2019
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Summary
This summary is machine-generated.

Implementing a dermatology specialist improved Kaposi sarcoma (KS) care by significantly reducing diagnostic delays. Quality improvement initiatives decreased histology turnaround times, crucial for timely treatment in Botswana.

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Area of Science:

  • Oncology
  • Dermatology
  • Public Health

Background:

  • Kaposi sarcoma (KS) is a prevalent HIV-associated skin cancer in Botswana, causing significant morbidity and mortality.
  • Diagnosis confirmation via histopathology is essential for chemotherapy but hindered by limited biopsy and pathology services.

Purpose of the Study:

  • To assess the impact of a dermatology specialist on improving Kaposi sarcoma care.
  • To evaluate the role of quality improvement (QI) initiatives in reducing histology turnaround times (TATs) for KS diagnosis.

Main Methods:

  • A retrospective review compared KS diagnoses and histology TATs before and after a dermatology specialist joined the public health system.
  • Patient data from January 2015–December 2015 (pre-QI) were compared with January 2016–November 2017 (post-QI).
  • A t test analyzed the difference in median histology TATs between the two periods.

Main Results:

  • 192 KS cases were diagnosed; 98.4% were HIV-positive, with a median age of 39.
  • Median histology TAT decreased from 32 days (pre-QI) to 11 days (post-QI) (P < .00).

Conclusions:

  • Dermatology-led QI initiatives effectively reduced histology TATs for Kaposi sarcoma.
  • Decreasing diagnostic delays is vital for reducing KS morbidity and mortality in resource-limited settings.