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A Dutch validation study of the Multiple Sclerosis Work Difficulties Questionnaire in relapsing remitting multiple
Elianne van Egmond1,2,3, Dennis van Gorp1,2,3,4, Cynthia Honan5
1National Multiple Sclerosis Foundation, Rotterdam, The Netherlands.
Disability and Rehabilitation
|November 9, 2019
Summary
The Dutch Multiple Sclerosis Work Difficulties Questionnaire-23 (MSWDQ-23) is a valid tool for assessing work challenges in individuals with MS. Higher scores on psychological and cognitive difficulties predict future employment status decline.
Area of Science:
- Rehabilitation Medicine
- Neuroscience
- Occupational Health Psychology
Background:
- Multiple Sclerosis (MS) significantly impacts employment.
- Accurate assessment of work difficulties is crucial for rehabilitation and support.
- Existing tools may require validation for specific populations, such as Dutch speakers with MS.
Purpose of the Study:
- To evaluate the psychometric properties of the Dutch version of the Multiple Sclerosis Work Difficulties Questionnaire-23 (MSWDQ-23).
- To establish the reliability and validity of the MSWDQ-23 for use in the Dutch MS population.
Main Methods:
- Confirmatory factor analysis was used to verify the factor structure of the MSWDQ-23.
- Construct validity was assessed by correlating MSWDQ-23 scores with measures of disability, fatigue, cognitive, neuropsychiatric, and quality of life variables.
- Predictive validity was determined using logistic regression to forecast employment status changes over one year.
Main Results:
- The Dutch MSWDQ-23 demonstrated acceptable internal consistency (α=0.913) and fair model fit.
- Construct validity was supported, with 94% of hypotheses confirmed.
- The MSWDQ-23 total scale and psychological/cognitive subscale predicted a decline in employment status after one year (p < 0.001).
Conclusions:
- The Dutch MSWDQ-23 is a reliable and valid instrument for measuring self-reported work difficulties in individuals with MS.
- Psychological and cognitive work challenges are significant predictors of future employment deterioration.
- The MSWDQ-23 serves as a valuable tool for clinicians and researchers to identify work difficulties and at-risk individuals with MS.

