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Multi-Modal Signals for Analyzing Pain Responses to Thermal and Electrical Stimuli
Published on: April 5, 2019
11.4K
New concepts of pain
Anne-Priscille Trouvin1, Serge Perrot1
1Unité INSERM U987, Hôpital Ambroise Paré, Paris Descartes University, 9 avenue Charles de Gaulle, 92100, Boulogne Billancourt, France; Centre d'Evaluation et Traitement de la Douleur, Hôpital Cochin, Paris Descartes University, 27 rue du Faubourg Saint Jacques, 75014, Paris, France.
Best Practice & Research. Clinical Rheumatology
|November 10, 2019
Summary
New pain research introduces nociplastic pain and refined classifications for musculoskeletal conditions like fibromyalgia and low back pain. Understanding central sensitization is key for persistent pain management.
Area of Science:
- Pain research
- Musculoskeletal pain
- Rheumatology
Background:
- Recent advancements in pain research are refining the understanding and classification of musculoskeletal pain.
- The International Association for the Study of Pain (IASP) has updated pain taxonomy, introducing 'nociplastic pain' as a third descriptor.
- The International Classification of Diseases, 11th Revision (ICD-11) now incorporates a new pain classification system developed by an IASP task force.
Purpose of the Study:
- To outline recent conceptual advancements in musculoskeletal pain research.
- To differentiate between primary and secondary musculoskeletal pain within the new ICD-11 framework.
- To explore the role of central sensitization in inflammatory rheumatic diseases with persistent pain.
Main Methods:
- Review of updated pain taxonomy and the ICD-11 classification system.
- Analysis of research discussing central sensitization in inflammatory rheumatic diseases.
- Examination of persistent pain states despite adequate biological treatment.
Main Results:
- Introduction of 'nociplastic pain' as a key concept in pain classification.
- Distinction between primary (e.g., fibromyalgia, low back pain) and secondary musculoskeletal pain.
- Growing evidence suggests central sensitization contributes to persistent pain in rheumatic diseases, even with effective treatments.
Conclusions:
- The evolving understanding of pain, including nociplastic pain and refined classifications, offers improved approaches for clinicians and researchers.
- Central sensitization is a significant factor in persistent pain experienced by patients with inflammatory rheumatic diseases, necessitating further investigation.
- These conceptual shifts are crucial for developing more targeted and effective pain management strategies.
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