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Published on: June 10, 2013
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A randomized pilot program to reduce opioid use following dental surgery and increase safe medication return
Karen J Derefinko1, Francisco I Salgado García1, Karen C Johnson1
1University of Tennessee Health Science Center, Department of Preventive Medicine, United States.
Addictive Behaviors
|November 10, 2019
Summary
A brief dental intervention significantly reduced opioid use post-surgery. This opioid misuse prevention program (OMPP) provided education and non-narcotic pain relievers, lowering morphine milligram equivalents (MMEs) compared to usual care.
Area of Science:
- Dental Surgery
- Pain Management
- Public Health
Background:
- Opioid prescriptions are linked to long-term use, with dentists being high prescribers.
- Dental practices are key sites for interventions to curb opioid misuse.
- Understanding the impact of cumulative opioid exposure is crucial for prevention.
Purpose of the Study:
- To evaluate the effectiveness of an opioid misuse prevention program (OMPP) in reducing opioid consumption after dental extraction surgery.
- To compare the OMPP intervention against a Treatment as Usual (TAU) control group.
Main Methods:
- A randomized clinical trial was conducted with 76 participants eligible for opioid medication.
- The OMPP group received a 10-minute educational counseling session and a 28-day supply of ibuprofen and acetaminophen.
- Follow-up assessments were conducted one week post-surgery.
Main Results:
- Intent-to-treat analysis (N=72) showed a non-significant trend (p=0.0835) where the OMPP group reported lower MMEs (37.94) than the TAU group (47.79).
- Sensitivity analysis excluding surgical complications (N=66) revealed a significant reduction in MMEs for the OMPP group (29.74 vs. 43.59, p=0.0259).
- The OMPP demonstrated a moderate effect size (d=0.42 to 0.56) in reducing self-reported opioid use.
Conclusions:
- A brief OMPP, including education and non-narcotic analgesics, shows promise in reducing opioid medication use following dental surgery.
- Targeted interventions in dental settings can effectively mitigate opioid consumption and potentially prevent long-term opioid dependence.
- Further research with larger sample sizes may confirm the significant impact of such preventive strategies.

