Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Coordination of Gene Expression Processes in Bacteria01:29

Coordination of Gene Expression Processes in Bacteria

526
The DNA replication, transcription, and translation processes are intricately coupled in bacteria, allowing efficient gene expression and rapid protein synthesis. While this physical and functional coordination is advantageous, it introduces challenges that bacteria overcome through specific regulatory mechanisms.Coupling of Replication, Transcription, and TranslationThe coupling of replication, transcription, and translation is a hallmark of bacterial gene expression. As the replisome unwinds...
526
Peptidoglycan Synthesis01:28

Peptidoglycan Synthesis

1.7K
Structure of PeptidoglycanPeptidoglycan is a vital structural component of the bacterial cell wall, providing mechanical strength and shape to the cell. It consists of repeating units of two sugars—N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM)—linked by β-1,4 glycosidic bonds. These sugar chains are cross-linked by short peptide chains, forming a mesh-like polymer that surrounds the bacterial plasma membrane.Cytoplasmic Phase – Precursor SynthesisPeptidoglycan...
1.7K
Protein Complexes with Interchangeable Parts01:57

Protein Complexes with Interchangeable Parts

2.8K
Groups of proteins may form a complex where each protein in this complex has a different role in the overall execution of the complex’s function. Often some of the proteins in the complex can be replaced by a closely related variant to give a complex that contains many of the same components yet is functionally distinct.
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order...
2.8K
Protein Complexes with Interchangeable Parts01:57

Protein Complexes with Interchangeable Parts

2.1K
2.1K
Yeast Signaling01:28

Yeast Signaling

17.0K
Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...
17.0K
Biosynthesis in Bacteria01:24

Biosynthesis in Bacteria

503
Biosynthesis in bacteria is a fundamental anabolic process that generates essential macromolecules, including proteins, nucleic acids, lipids, and polysaccharides. These macromolecules are critical for cellular growth, replication, and function. The process is tightly regulated and energetically linked to catabolic pathways to ensure optimal resource utilization.Biosynthetic pathways begin with precursor metabolites such as pyruvate, acetyl-CoA, and glucose-6-phosphate derived from glycolysis,...
503

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SGLT2 inhibitor use reduces progression and surgical intervention of persistent pulmonary nodules.

Lung cancer (Amsterdam, Netherlands)·2026
Same author

Surgical impact of pafolacianine-based intraoperative molecular imaging in lobar versus sublobar pulmonary resection.

JTCVS techniques·2025
Same author

Survival of Thermostable Φ6 Genotypes in Acidic, Basic, and UV Environments.

bioRxiv : the preprint server for biology·2025
Same author

Experimental Evolution Studies in Φ6 Cystovirus.

Viruses·2024
Same author

Novel intraoperative near-infrared imaging strategy to identify abnormalities in the anterior mediastinum.

Journal of cardiothoracic surgery·2022
Same author

Effects of historical co-infection on host shift abilities of exploitative and competitive viruses.

Evolution; international journal of organic evolution·2021

Related Experiment Video

Updated: Jan 4, 2026

Fluorescence Time-lapse Imaging of the Complete S. venezuelae Life Cycle Using a Microfluidic Device
11:30

Fluorescence Time-lapse Imaging of the Complete S. venezuelae Life Cycle Using a Microfluidic Device

Published on: February 28, 2016

14.3K

Digest: Structuring interactions in Streptomyces.

Sonia Singhal1

  • 1Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, 27599.

Evolution; International Journal of Organic Evolution
|November 10, 2019
PubMed
Summary

Spatial structure benefits antibiotic production in bacterial colonies. This structure amplifies the advantage of streptomycin production by Streptomyces griseus against susceptible competitors, especially when resistance is low.

More Related Videos

Visual and Microscopic Evaluation of Streptomyces Developmental Mutants
08:42

Visual and Microscopic Evaluation of Streptomyces Developmental Mutants

Published on: September 12, 2018

18.7K
A High-Yield Streptomyces Transcription-Translation Toolkit for Synthetic Biology and Natural Product Applications
07:59

A High-Yield Streptomyces Transcription-Translation Toolkit for Synthetic Biology and Natural Product Applications

Published on: September 10, 2021

4.6K

Related Experiment Videos

Last Updated: Jan 4, 2026

Fluorescence Time-lapse Imaging of the Complete S. venezuelae Life Cycle Using a Microfluidic Device
11:30

Fluorescence Time-lapse Imaging of the Complete S. venezuelae Life Cycle Using a Microfluidic Device

Published on: February 28, 2016

14.3K
Visual and Microscopic Evaluation of Streptomyces Developmental Mutants
08:42

Visual and Microscopic Evaluation of Streptomyces Developmental Mutants

Published on: September 12, 2018

18.7K
A High-Yield Streptomyces Transcription-Translation Toolkit for Synthetic Biology and Natural Product Applications
07:59

A High-Yield Streptomyces Transcription-Translation Toolkit for Synthetic Biology and Natural Product Applications

Published on: September 10, 2021

4.6K

Area of Science:

  • Microbiology
  • Evolutionary Biology
  • Ecology

Background:

  • Bacterial colonies exhibit spatial structures that can support costly traits like antibiotic production.
  • The bacterium Streptomyces griseus produces streptomycin, an antibiotic that impacts competing bacterial strains.

Discussion:

  • Westhoff et al. investigated the advantages of streptomycin production in spatially structured environments.
  • Competition dynamics between Streptomyces griseus and a streptomycin-susceptible strain were analyzed.
  • The study explored how competitor resistance to streptomycin affects the benefits of antibiotic production.

Key Insights:

  • Streptomyces griseus successfully outcompeted susceptible strains in spatially structured environments.
  • The efficacy of streptomycin decreased as the competitor's resistance to the antibiotic increased.
  • Spatial structure enhanced the invasion capability of Streptomyces griseus into susceptible populations, even from low initial densities.

Outlook:

  • Spatially structured microbial communities can provide and magnify the benefits of antibiotic production.
  • Understanding these dynamics is crucial for microbial ecology and evolution.
  • Further research could explore other costly traits maintained by spatial structuring in microbial populations.