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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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Tumor Immunotherapy01:27

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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The Tumor Microenvironment02:17

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
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Related Experiment Video

Updated: Jan 4, 2026

A Brain Tumor/Organotypic Slice Co-culture System for Studying Tumor Microenvironment and Targeted Drug Therapies
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Targeting Mindsets, Not Just Tumors.

Sean R Zion1, Lidia Schapira2, Alia J Crum1

  • 1Department of Psychology, Stanford University, Stanford, CA, USA.

Trends in Cancer
|November 11, 2019
PubMed
Summary
This summary is machine-generated.

Mindsets, or core beliefs, significantly impact cancer patients' mental and physical health. Developing targeted psychological interventions to foster adaptive mindsets can revolutionize cancer supportive care.

Keywords:
cancerinterventionmindsetpsychological supportquality of life

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Area of Science:

  • Psychology
  • Oncology
  • Health Psychology

Background:

  • Mindsets, defined as core assumptions, are understudied in cancer care.
  • These assumptions can significantly influence patient well-being.

Purpose of the Study:

  • To highlight the critical role of mindsets in cancer patient health.
  • To explore the potential of psychological interventions for improving supportive care.

Main Methods:

  • Review of existing literature on mindsets and health outcomes.
  • Conceptual analysis of psychological intervention strategies.

Main Results:

  • Mindsets are a key variable affecting both mental and physical health in cancer patients.
  • Adaptive mindsets show promise for enhancing patient outcomes.

Conclusions:

  • Targeted psychological interventions focused on adaptive mindsets can transform supportive care.
  • Further research into mindset interventions is warranted for oncology settings.