Transtail Artery Access in Rats: A New Technique for Repeatable Selective Angiography
Kosuke Kumagai1, Masahiro Horikawa2, Kentaro Yamada2
1Dotter Department of Interventional Radiology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR; Department of Neurosurgery, National Defense Medical College, Tokorozawa, Japan.
Journal of Vascular and Interventional Radiology : JVIR
|November 11, 2019
Summary
A novel transtail artery approach allows for precise arterial catheterization and angiography in rats. This effective and repeatable technique has potential applications in transcatheter therapies and stroke research.
Area of Science:
- Veterinary Medicine
- Surgical Techniques
- Diagnostic Imaging
Background:
- Selective arterial catheterization is crucial for various preclinical research applications.
- Existing methods for arterial access in rodents can be challenging and invasive.
- Developing minimally invasive and effective techniques is essential for advancing animal research.
Purpose of the Study:
- To introduce and evaluate a novel transtail artery approach for selective arterial catheterization in rats.
- To assess the efficacy, repeatability, and potential applications of this new technique.
Main Methods:
- A transtail artery approach was utilized for catheter insertion and selective arterial access in a rat model.
- Angiography was performed to visualize arterial structures and confirm catheter placement.
- The technique's effectiveness and repeatability were assessed through multiple procedures.
Main Results:
- Successful selective arterial catheterization and angiography were achieved using the transtail artery approach.
- The technique demonstrated high efficacy and repeatability in the rat model.
- No significant complications were reported during the procedures.
Conclusions:
- The transtail artery approach is a viable and effective method for selective arterial catheterization and angiography in rats.
- This technique offers a minimally invasive option with potential for transcatheter therapies and cerebral stroke modeling.
- Further research is warranted to explore the full scope of its applications in preclinical studies.
