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Streptococcus intermedius masquerading as fungal infective endocarditis
A Salem1, S Azeez2, J Stirrup3
1Specialist Registrar in Cardiology, Department of Cardiology, Milton Keynes University Hospital, Milton Keynes MK9 1LA.
Infective endocarditis caused by Streptococcus intermedius is rare and challenging to diagnose. Molecular testing, specifically 16S polymerase chain reaction, proved crucial for identifying this difficult-to-culture organism in a recent case.
Area of Science:
- Infectious Diseases
- Microbiology
- Cardiology
Background:
- Infective endocarditis (IE) presents a significant clinical challenge with high morbidity and mortality.
- Difficulties in pathogen identification, especially for non-culturable organisms, hinder timely diagnosis and treatment.
- Streptococcus intermedius, a member of the S. milleri group, is a rare cause of IE and can mimic fungal infections.
Related Concept Videos
Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis III: Medical Management
Endocarditis IV: Nursing Management
Myocarditis I: Introduction
Myocarditis II: Clinical Features and Diagnostic Tests

