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Patient-reported outcomes: Which ones are most relevant?

Esther M M Van Lieshout1, Mathieu M E Wijffels1

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Patient-reported outcome measures (PROs) are crucial in orthopedic trauma research and care. This review guides selecting and using PROs effectively to enhance patient outcomes and research validity.

Keywords:
OutcomePROPatient-reported outcomeReliabilityResponsivenessValidity

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Area of Science:

  • Orthopedic Surgery
  • Clinical Research Methodology
  • Patient-Reported Outcomes

Background:

  • Patient-reported outcome measures (PROs) usage is rapidly increasing in orthopedic trauma surgery.
  • Standardized methods for PRO selection and application are needed.

Purpose of the Study:

  • To provide guidance on identifying, reviewing, selecting, and utilizing PROs in orthopedic trauma research and clinical practice.
  • To ensure the quality and validity of PRO data in orthopedic trauma studies.

Main Methods:

  • Systematic literature review to identify commonly used PRO instruments.
  • Evaluation of instrument measurement properties based on COSMIN standards.
  • Consideration of readability, usability, and cost during selection.
  • Assessment of translation and validation procedures for non-native languages.
  • Adherence to reporting guidelines like SPIRIT-PRO and CONSORT-PRO.

Main Results:

  • A systematic approach to PRO selection ensures instruments are valid for the specific condition, intervention, and population.
  • High-quality PRO measurement properties are essential for reliable research findings.
  • Utilizing Core Outcome Sets enhances research validity and meta-analysis feasibility.

Conclusions:

  • Implementing standardized procedures for PRO identification, selection, and use improves orthopedic trauma research quality.
  • Properly applied PROs contribute to enhanced patient care and more robust clinical research.
  • Adherence to established guidelines and quality standards is key for maximizing the value of PROs.