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Phaeohyphomycosis caused by Phialophora richardsiae.
1Department of Dermatology, Faculty of Medicine, Kyoto University, Japan.
Journal of the American Academy of Dermatology
|September 1, 1988
Summary
A rare fungal infection, phaeohyphomycosis caused by Phialophora richardsiae, occurred in an immunocompromised patient. This case highlights the challenges in diagnosing and treating this emerging mycosis in Japan.
Area of Science:
- Medical Mycology
- Infectious Diseases
Background:
- Phaeohyphomycosis is a fungal infection caused by dematiaceous molds.
- Phialophora richardsiae is a rare agent of phaeohyphomycosis, particularly in immunocompromised individuals.
Observation:
- A 30-year-old male with end-stage malignant lymphoma developed a recurrent subcutaneous abscess on his right foot.
- The abscess was surgically removed but rapidly recurred.
Findings:
- The causative agent, Phialophora richardsiae, was isolated from the abscess pus.
- This represents the fifth documented case of phaeohyphomycosis due to P. richardsiae globally.
- This is the first reported case of P. richardsiae-induced phaeohyphomycosis in Japan.
Implications:
- This case expands the known geographical distribution of P. richardsiae infections.
- It underscores the importance of considering rare fungal pathogens in immunocompromised patients with persistent infections.
- Early diagnosis and appropriate management are crucial for successful treatment outcomes.