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Role of trace elements in pityriasis Alba

Ghada M Khafagy1, Hanan R Nada2, Laila A Rashid3

  • 1Department of Family Medicine, Faculty of Medicine, Cairo University, Egypt.

Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)
|November 12, 2019
PubMed

Insights

Pityriasis Alba (PA) in children is linked to lower levels of hemoglobin, zinc, copper, and magnesium. Sun exposure and skin type are also identified as key risk factors for this common skin condition.

Area of Science:

  • Pediatric Dermatology
  • Nutritional Biochemistry
  • Clinical Research

Background:

  • Pityriasis Alba (PA) is a prevalent pediatric skin condition with various contributing factors.
  • Understanding the biochemical profile associated with PA is crucial for effective management.

Purpose of the Study:

  • To investigate serum levels of trace elements (copper, zinc, magnesium) and hemoglobin (Hb) in children diagnosed with Pityriasis Alba.
  • To identify potential nutritional deficiencies and their correlation with PA.

Main Methods:

  • A case-control study involving 110 children (55 with PA, 55 controls) aged 6-16.
  • Analysis of sociodemographic data, clinical history, and dermatological examination.
  • Biochemical assessment of serum trace elements and hemoglobin levels using SPSS software.

Main Results:

  • Significantly lower levels of hemoglobin, serum ferritin, copper, zinc, and magnesium were observed in the PA group compared to controls.
  • Zinc deficiency was associated with a >15-fold increased risk of PA.
  • Reduced Hb levels increased PA risk by over ninefold (OR 9.6).

Conclusions:

  • Pityriasis Alba is associated with deficiencies in hemoglobin, serum zinc, ferritin, copper, and magnesium.
  • Sun exposure and skin phototype are significant risk factors for developing PA.
  • These findings highlight the importance of nutritional status and environmental factors in PA pathogenesis.
Abstract

Keywords:
AtopyFamily practicePityriasis AlbaTrace elements

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