Incidence and risk factors for recurrent cardiovascular disease in middle-eastern adults: a retrospective study

Romona D Govender1, Saif Al-Shamsi2, Elpidoforos S Soteriades3

  • 1College of Medicine and Health Sciences, Department of Family Medicine, United Arab Emirates University, P.O. Box 17666, Al Ain, United Arab Emirates. govenderr@uaeu.ac.ae.

Insights

Recurrent cardiovascular events are common in the UAE. Older age, female sex, and diabetes mellitus significantly predict these events, highlighting the need for targeted preventive strategies in the United Arab Emirates population.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Cardiovascular disease (CVD) poses a significant health burden globally, with high rates of recurrent events and mortality.
  • The United Arab Emirates (UAE) exhibits one of the highest age-standardized death rates for CVD worldwide.
  • Established CVD patients with risk factors face elevated risks of subsequent cardiovascular events and mortality.

Purpose of the Study:

  • To determine the incidence rates of recurrent CVD events among UAE nationals.
  • To identify key predictors of recurrent CVD events within this population.

Main Methods:

  • An outpatient-based cohort study was conducted involving patients with a history of CVD.
  • Follow-up extended for a median of 8.1 years, utilizing univariable and multivariable Cox proportional hazards regression models.
  • Analysis focused on the association between major CVD risk factors and the risk of CVD recurrence.

Main Results:

  • The study included 216 patients (167 males, 49 females) with a total of 1184 patient-years of follow-up.
  • The overall incidence rate of recurrent CVD events was 92.1 per 1000 patient-years, with an 8-year cumulative incidence of 73.7%.
  • Significant predictors identified were older age, female sex (1.96 times higher risk than males), and diabetes mellitus.

Conclusions:

  • Older age, female sex, and diabetes mellitus are significant predictors of recurrent CVD events in UAE nationals.
  • The high incidence rate underscores the need for enhanced preventive measures.
  • Implementing international guidelines for CVD management may reduce morbidity and mortality in the UAE.
Abstract

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