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Interarytenoid botulinum toxin A injection for the treatment of vocal process granuloma
A-L Hamdan1, E Khalifee1, H Jaffal1
1Department of Otorhinolaryngology Head and Neck Surgery, American University of Beirut Medical Center, Lebanon.
Objectives:
To report on the efficacy and adverse effects of interarytenoid botulinum toxin A injection for the treatment of vocal process granuloma.
Methods:
A retrospective chart review was conducted of eight patients with vocal process granuloma resistant to anti-reflux therapy who underwent interarytenoid botulinum toxin A injection. The mean dosage of botulinum toxin A injected was 6.56 U.
Results:
Fifty per cent of patients had complete regression of the lesion and 50 per cent had partial regression. The main side effects were breathiness (n = 4), voice breaks (n = 1) and aspiration (n = 1).
Conclusion:
Interarytenoid botulinum toxin A injection for the treatment of vocal process granuloma is an effective mode of therapy, with transient vocal and swallowing side effects.
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