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Neurophysiological changes and chronic pain in cleft patients
Amely Hartmann1, Claudia Welte-Jzyk2, Bilal Al-Nawas2
1Private Practice for Oral and Maxillofacial Surgery, Private Practice Dr. Seiler and Colleagues, Echterdinger Straße 7, 70794 Filderstadt, Germany.
Summary
Patients with orofacial clefts (CLP) often experience chronic pain and neurophysiological changes post-surgery. Early pain and psychological management is crucial to mitigate these risks in CLP patients.
Area of Science:
- Oral and Maxillofacial Surgery
- Pain Medicine
- Neuroscience
Background:
- Orofacial cleft repair (CLP) can lead to long-term complications.
- Chronic pain and neurophysiological alterations are potential sequelae of CLP surgery.
Purpose of the Study:
- To investigate neurophysiological changes and chronic pain states in patients following orofacial cleft repair.
- To assess the quality of life and psychological comorbidities in CLP patients.
Main Methods:
- A survey of 48 patients with repaired orofacial clefts using five questionnaires.
- Assessment of pain states, quality of life (OHIP), psychological comorbidity (GSCL, HADS), and psychosocial impairment.
- Evaluation of neurophysiological perception to thermal and tactile stimuli.
Main Results:
- 39 out of 48 CLP patients reported pain in the last 6 months; 36 had chronic pain.
- Pain localized to orofacial region, back, and limbs; inhomogeneous neurophysiological perception observed.
- Elevated anxiety and depression levels noted; increased local analgesia required during dental procedures.
Conclusions:
- CLP patients have a higher risk of developing chronic pain and neurophysiological disturbances.
- Early and comprehensive pain and psychological management is recommended for CLP patients.
- Further research with neurophysiological diagnostic tools is warranted.
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