Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.1K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.1K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

909
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
909

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Autograft versus Allograft in Indirect Corneal Neurotization: A Systematic Review.

American journal of ophthalmology·2026
Same author

A cost-effectiveness analysis of medications compared with selective laser trabeculoplasty in patients with newly diagnosed open-angle glaucoma.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
Same author

Age-related macular degeneration associated with glucagon-like peptide-1 receptor agonist use: a systematic review.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
Same author

Diabetic macular edema and GLP-1 receptor agonist use: a systematic review and meta-analysis.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
Same author

Corneal pyogenic granuloma on eye with limbal stem cell deficiency.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
Same author

Examining the impact on quality-of-life of those living with inherited optic neuropathies: an updated systematic review.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026

Related Experiment Video

Updated: Jan 4, 2026

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
05:14

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter

Published on: September 16, 2025

512

Dry eye after refractive surgery: a meta-analysis.

Raman-Deep Singh Sambhi1, Gagan Deep Singh Sambhi2, Rookaya Mather3

  • 1Schulich School of Medicine and Dentistry, Western University, London, Ont.

Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie
|November 13, 2019
PubMed
Summary
This summary is machine-generated.

Laser-assisted in situ keratomileusis (LASIK) significantly reduces tear production and tear break-up time (TBUT), while other refractive surgeries like small incision lenticule extraction (SMILE) show nonsignificant changes. More research is needed for definitive conclusions on dry eye after refractive surgery.

More Related Videos

Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits
07:43

Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits

Published on: January 8, 2020

10.8K
Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases
07:36

Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases

Published on: July 3, 2025

557

Related Experiment Videos

Last Updated: Jan 4, 2026

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
05:14

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter

Published on: September 16, 2025

512
Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits
07:43

Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits

Published on: January 8, 2020

10.8K
Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases
07:36

Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases

Published on: July 3, 2025

557

Area of Science:

  • Ophthalmology
  • Refractive Surgery
  • Dry Eye Disease

Background:

  • Dry eye is a common concern following refractive surgery.
  • Different surgical techniques may impact ocular surface homeostasis differently.

Purpose of the Study:

  • To compare the incidence and severity of dry eye symptoms after various refractive surgeries.
  • To analyze the impact of laser-assisted in situ keratomileusis (LASIK), photorefractive keratectomy (PRK), femtosecond lamellar extraction (FLEx), and small incision lenticule extraction (SMILE) on dry eye parameters.

Main Methods:

  • A systematic review and meta-analysis was performed adhering to PRISMA guidelines.
  • Extensive database searches were conducted across multiple scientific literature repositories.
  • Data from 14 selected studies were extracted and analyzed for tear break-up time (TBUT) and tear production.

Main Results:

  • LASIK demonstrated a significant reduction in both TBUT (SMD = -0.3) and tear production (SMD = -0.23).
  • FLEx showed a significant reduction in TBUT (SMD = -1.09) but not tear production (SMD = -0.05).
  • SMILE and PRK exhibited nonsignificant reductions in both TBUT and tear production.

Conclusions:

  • LASIK is associated with significant postoperative dry eye, affecting tear production and TBUT.
  • SMILE, FLEx, and PRK appear to have a less pronounced, nonsignificant impact on these dry eye parameters.
  • High-quality randomized controlled trials are necessary to establish definitive conclusions regarding dry eye after refractive surgery.