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Related Concept Videos

Non-LTR Retrotransposons03:18

Non-LTR Retrotransposons

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As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...
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Related Experiment Video

Updated: Jan 4, 2026

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
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[Multiple recurrent retroperitoneal liposarcoma in a 66-year-old man].

I Niemetz1, J Faß2, M Wolf3

  • 1, Postfach 10 27 06, 34027, Kassel, Deutschland. info@internisten-kassel.de.

Der Internist
|November 13, 2019
PubMed
Summary
This summary is machine-generated.

This case study details a patient with eight recurrences of retroperitoneal liposarcoma over 17 years. Despite multiple treatments, the patient maintained a good general condition, highlighting the potential for long-term management of this rare cancer.

Keywords:
Chemotherapy, adjuvantHemocolectomyNeoplasms, connective and soft tissueQuality of lifeRetroperitoneal liposarcoma, recurrence

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Area of Science:

  • Oncology
  • Surgical Pathology

Background:

  • Retroperitoneal liposarcoma is a rare malignant tumor.
  • Recurrence is common, necessitating aggressive management.

Observation:

  • A 66-year-old male presented with his first retroperitoneal liposarcoma recurrence 7 years post-diagnosis.
  • Over the next 10 years, he underwent eight surgical operations, chemotherapy, and radiotherapy for seven additional recurrences.

Findings:

  • This case represents the first documented instance of eight recurrences of retroperitoneal liposarcoma in a single patient.
  • Remarkably, the patient remained in relatively good general condition 17 years after his initial diagnosis.

Implications:

  • This case underscores the possibility of long-term survival and management of recurrent retroperitoneal liposarcoma.
  • It highlights the importance of multidisciplinary treatment approaches for complex cases of retroperitoneal liposarcoma.