[Keratoplasty in children : Indications and results]

S J Lang1, D Böhringer2, T Reinhard2

  • 1Klinik für Augenheilkunde, Medizinische Fakultät, Universitätsklinikum Freiburg, Kilianstr. 5, 79106, Freiburg, Deutschland. stefan.lang@uniklinik-freiburg.de.

Insights

Penetrating keratoplasty in children presents unique surgical challenges and requires careful consideration of pediatric-specific indications. Optimal timing is crucial to balance graft survival against the risk of amblyopia.

Area of Science:

  • Ophthalmology
  • Pediatric Surgery
  • Corneal Surgery

Background:

  • Penetrating keratoplasty (PK) in children involves unique challenges compared to adults.
  • Pediatric indications, examination difficulties, and parental adherence impact surgical outcomes.
  • Age is a risk factor, likely due to follow-up examination and compliance issues.

Purpose of the Study:

  • To outline the specific challenges and considerations for performing penetrating keratoplasty in pediatric patients.
  • To identify factors influencing graft survival and visual prognosis in children undergoing PK.
  • To emphasize the critical role of surgical timing in pediatric corneal transplantation.

Main Methods:

  • Review of pediatric-specific indications for penetrating keratoplasty.
  • Analysis of factors affecting graft survival, including age and underlying ocular conditions.
  • Discussion of the risk-benefit analysis concerning graft survival and amblyopia prevention.

Main Results:

  • Favorable prognoses are seen in keratoconus and herpetic keratitis.
  • Sclerocornea and Peters' anomaly often have limited visual and graft survival prognosis due to ocular malformations.
  • Younger age is associated with increased risk, linked to examination and compliance challenges.

Conclusions:

  • Successful pediatric penetrating keratoplasty requires addressing unique challenges in indications, examination, and adherence.
  • Careful patient selection and management are vital, especially for conditions like sclerocornea and Peters' anomaly.
  • The timing of surgery is paramount, balancing graft success with the critical risk of amblyopia development.

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