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Ion Manipulation in Open Air Using 3D-Printed Electrodes.

Kiran Iyer1, Brett M Marsh1, Grace O Capek1

  • 1Department of Chemistry, Purdue University, West Lafayette, IN, 47907, USA.

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|November 13, 2019
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Summary
This summary is machine-generated.

3D-printed focusing devices improve ion transfer for ambient ionization mass spectrometry. These devices, made from carbon nanotube polymers, enhance ion collection efficiency by optimizing ion trajectories in air, even at high pressures.

Keywords:
Additive manufacturingAmbient ionizationIon focusingIon transmissionTriple quadrupole

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Area of Science:

  • Analytical Chemistry
  • Materials Science

Background:

  • Ambient ionization techniques enable direct sampling of materials in air.
  • Ion transfer and focusing typically require reduced pressure environments, limiting efficiency.
  • Spray-based ambient ionization sources face challenges with ion collection over large distances.

Purpose of the Study:

  • To develop and evaluate 3D-printed focusing devices for enhanced ion transfer in ambient ionization mass spectrometry.
  • To investigate the impact of electrode geometry and material on ion focusing in atmospheric pressure.
  • To assess the efficiency of ion collection and beam collimation at high pressures.

Main Methods:

  • Design and fabrication of 3D-printed electrodes using conductive carbon nanotube doped polymers.
  • Simulation of ion trajectories using the statistical diffusion simulation (SDS) model in SIMION.
  • Experimental evaluation using an ion detecting charge-coupled device (IonCCD) and mass spectrometry.

Main Results:

  • Electrode geometry significantly influences ion trajectories and focusing efficiency.
  • Both conductive and non-conductive electrodes, including complex geometries, demonstrated focusing capabilities.
  • Minimal ion beam spreading was observed post-focusing, indicating effective collimation at atmospheric pressure.

Conclusions:

  • 3D-printed focusing devices offer a promising solution for efficient ion transfer in ambient ionization mass spectrometry.
  • High-pressure environments can be leveraged for, rather than be a hindrance to, ion transport.
  • The study highlights the potential of advanced materials and additive manufacturing in improving mass spectrometry performance.