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Published on: June 12, 2021
Plasmapheresis in Patients With Heparin-induced Thrombocytopenia Requiring Ventricular Assist Device
Salvador R Maffei1, Harveen K Lamba2, Cassius Kwasi Mensah2
1Division of Cardiothoracic Transplantation and Circulatory Support, Baylor College of Medicine, Houston, Texas.
Anticoagulation with unfractionated heparin is vital to reduce the risk of thromboembolic events during cardiopulmonary bypass and left ventricular assist device placement. However patients with heparin-induced thrombocytopenia are at risk of developing immune-mediated thrombotic events. We describe 2 patients with heparin-induced thrombocytopenia confirmed via serotonin release assay who were successfully treated with plasmapheresis exchange before left ventricular assist device placement.
Anticoagulation with unfractionated heparin is vital to reduce the risk of thromboembolic events during cardiopulmonary bypass and left ventricular assist device placement. However patients with heparin-induced thrombocytopenia are at risk of developing immune-mediated thrombotic events. We describe 2 patients with heparin-induced thrombocytopenia confirmed via serotonin release assay who were successfully treated with plasmapheresis exchange before left ventricular assist device placement.
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