Maternal Mental Illness Is Associated with Adverse Neonate Outcomes: An Analysis of Inpatient Data

Objective: Addressing mental illness and associated outcomes is a major public health priority in the United States. In this study, our goal was to assess the role of maternal mental illness and its association to poor fetal growth and preterm delivery in one of the most socioeconomically disadvantaged areas of California. Methods: Data were obtained from the public database of California inpatient data from the Office of Statewide Health Planning and Development (OSHPD). OSHPD provides de-identified data on all inpatient department visits within California, to ensure confidentially of patients. Each variable was dichotomized into a binary variable of presence or absence of diagnosis status. The primary independent variable was clinical diagnosis of any mental illness. The dependent variables were pregnancy birth outcomes defined as poor fetal growth and preterm delivery. We specifically focused on inland Southern California due to its higher socioeconomic burden and poor maternal-child outcomes. Results: In the inland Southern California area, which is generally a geographic location with high poverty, maternal mental illness was associated with 79% higher odds of poor fetal growth and 64% higher odds of preterm delivery. Increasing numbers of co-morbidities were also associated with poor fetal growth. On the other hand, being older, being on Medicaid or other insurance status, being non-Hispanic Black, as well as increasing co-morbidities were associated with increased odds of preterm delivery. Conclusions: The purpose of the study was to evaluate the immediate birth outcomes associated with maternal mental illness. Given the empirical evidence of the study, addressing maternal mental health status is a key public health issue, especially in socioeconomically disadvantaged areas.