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Author Spotlight: Assessing the Impact of Novel Iron Chelators on Cancer Cell Metabolism
Published on: February 23, 2024
A novel polythioether-based rhodamine B fluorescent probe via successive click reaction and its application in iron
Xiaomei Zhang1, Zhiming Gou1, Yujing Zuo1
1Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Shandong, 250022, PR China.
Abstract:
Polythioether has good chemical stability and biocompatibility and is a kind of promising polymers for the application of optical materials, medical materials and energy conversion materials. However, the fluorescent probe based on polythioether is still rare. Herein, a series of polythioether based polymer fluorescent probes were synthesized by successive thiol click reaction under ultraviolet light at room temperature. The poly(thioether)s have good selectivity and responsiveness to iron ions and can be applied in cell imaging, which indicate that the broad application prospects of polythioether-based fluorescent probes in ion detection and bioimaging.

