Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

SpaceMed: Immersive interdisciplinary academic training for the future of human space exploration.

Experimental physiology·2026

Same author

Housing modifications for heat adaptation, thermal comfort and malaria vector control in rural African settlements.

Nature medicine·2026

Same author

Brain power comparison between microgravity and head-down tilt bed rest: an electroencephalography approach.

Scientific reports·2025

Same author

Assessing heat exposure and its effects on farmer health, harvest yields, and nutrition: a study protocol for Burkina Faso and Kenya.

Global health action·2025

Same author

Transient gray matter decline during antarctic isolation: Roles of sleep, exercise, and cognition.

NPJ microgravity·2025

Same author

Impact of peripheral skin cooling on neuroendocrine leukocytic and hematological reactions during Hypergravity.

NPJ microgravity·2025

Search research articles

Related Experiment Video

Updated: Jan 4, 2026

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection

Published on: August 26, 2011

Electrocortical Evidence for Impaired Affective Picture Processing after Long-Term Immobilization.

Katharina Brauns¹, Anika Werner^1,2, Hanns-Christian Gunga¹

¹Charité - Universitätsmedizin Berlin, a corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Physiology, Charitéplatz 1, CharitéCrossOver, Virchowweg 6, 10117, Berlin, Germany.

Scientific Reports

|November 14, 2019

Summary

Thirty days of head-down tilt bed rest, a spaceflight analogue, reduced emotional brain responses in healthy men. This suggests potential neurobehavioral risks for astronauts affecting emotion regulation.

More Related Videos

Brain Imaging Investigation of the Impairing Effect of Emotion on Cognition

Brain Imaging Investigation of the Impairing Effect of Emotion on Cognition

Published on: February 1, 2012

Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion

Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion

Published on: May 4, 2011

Related Experiment Videos

Last Updated: Jan 4, 2026

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection

Published on: August 26, 2011

Brain Imaging Investigation of the Impairing Effect of Emotion on Cognition

Brain Imaging Investigation of the Impairing Effect of Emotion on Cognition

Published on: February 1, 2012

Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion

Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion

Published on: May 4, 2011

Area of Science:

Neuroscience
Space Medicine
Psychophysiology

Background:

Spaceflight poses neurobehavioral risks, with limited understanding of resilience, social processes, and emotion regulation.
Head-down tilt bed rest simulates spaceflight's physical inactivity, isolation, and confinement.

Purpose of the Study:

To investigate the effects of 30-day bed rest on affective picture processing using event-related potentials (ERPs).
To explore neurophysiological changes in emotion regulation during simulated long-duration spaceflight.

Main Methods:

Healthy men underwent 30 days of 6-degree head-down tilt bed rest.
Event-related potentials (ERPs), specifically P300 and Late Positive Potential (LPP) amplitudes, were measured during affective picture viewing.
Source localization was used to identify brain regions with altered activity.

Main Results:

Bed rest participants exhibited significantly decreased P300 and LPP amplitudes to emotional stimuli compared to controls.
These reductions were most pronounced in centroparietal regions.
Source localization indicated reduced activity in the posterior cingulate gyrus, insula, and precuneus for emotional stimuli in the bed rest group.

Conclusions:

30-day bed rest significantly alters affective picture processing, indicated by reduced ERP amplitudes and decreased activity in key brain regions.
These findings highlight potential neurophysiological changes impacting emotion regulation during simulated spaceflight.
Further research is needed to understand and mitigate these neurobehavioral risks for astronauts.