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Updated: Jan 4, 2026

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Extrahepatic Vascular Parasitization by a Hepatocellular Carcinoma
Marco Ertreo1, Daniel R Swerdlow2, Alexander Kim1
1Vascular and Interventional Radiology, Medstar Georgetown University Hospital, Washington, DC, USA.
Abstract:
Hepatocellular carcinoma is the most common primary hepatic malignancy. For patients not amenable to surgical treatment, transarterial chemoembolization is a viable therapeutic alternative. Extrahepatic collateral arterial supply to the tumor may occur in a variety of scenarios and timely detection of this phenomenon is of fundamental importance to achieve optimal outcomes and response to treatment. This report presents a case of hepatocellular carcinoma that was supplied mainly by a parasitized right phrenic artery and was only successfully treated once this was identified. Further discussion of extrahepatic collateral arterial supply is also presented.
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