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Updated: Jan 3, 2026

Porphyromonas gingivalis as a Model Organism for Assessing Interaction of Anaerobic Bacteria with Host Cells
Published on: December 17, 2015
[Research progress on the relationship between Porphyromonas gingivalis and the malignancy of the digestive system
Chun-Meng Wang1, Li-Hua Hong1, Zhi-Min Zhang1
1Dept. of Endodontics, School and Hospital of Stomatology, Jilin University, Changchun 130021, China.
Abstract:
The malignant tumors including oral cancer, colorectal cancer, pancreatic cancer, and esophageal cancer, of the digestive system are a common high-fatal malignancy. Porphyromonas gingivalis, as the most important pathogen of periodontal disease, has been gradually proved that its invasiveness occurs not only in the mouth but also in other parts of the digestive system. Moreover, the relevant pathogenic mechanism is increasingly attracting the reseachers' attention. In this study, the role and possible pathogenesis of Porphyromonas gingivalis in the digestive system are described in a systematic and comprehensive way.

