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[Expression of myofibroblast in gingival after orthodontic loading]
Yao Meng1, Man Liu2, Qian-Nan Deng1
1Dept. of Orthodontics, Shenzhen Children's Hospital, Shenzhen 518000, China.
Objective:
To examine the expression of myofibroblast in gingival after orthodontic loading.
Methods:
Eight patients were selected as experimental group and treated with orthodontic force for 4 months. Ten patients were selected as the control group, were not loaded. The gingival protein expressions of collagen typeⅠ, collagen type Ⅲ, α-smooth muscle actin (α-SMA) were evaluated by immunohistochemistry method.
Results:
Positive expressions of collagen typeⅠ, collagen type Ⅲ were founded, while no positive staining for α-SMA in the gingival tissue except vascular epithelium before loading. In experimental group, collagen type I and collagen type Ⅲ were increased after orthodontic loading (P<0.05), the expression of α-SMA was detected and statistically significant (P<0.05).
Conclusions:
The myofibroblast exists in gingival tissue after orthodontic loading, and it may be concerned with orthodontic teeth relapse.
