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[ACUTE RENAL FAILURE INDUCED BY METAMIZOLE]

Inbal Greenhouse1, Shani Attia-Konyo1, Meir Mouallem1

  • 1Department of Medicine E, Sheba Medical Center, Tel-Hashomer, affiliated to Sackler Faculty of Medicine, Tel-Aviv University, Israel.

Harefuah
|November 14, 2019
PubMed
Abstract

Insights

Sodium metamizole (Optalgin), a common pain reliever, can cause acute kidney injury. This case highlights the importance of recognizing metamizole

Area of Science:

  • Nephrology
  • Pharmacology

Background:

  • Sodium metamizole (Optalgin) is a widely used analgesic and antipyretic in Israel.
  • Its prevalence necessitates a thorough understanding of potential adverse effects.

Observation:

  • A case of acute kidney injury (AKI) is presented in a young, otherwise healthy patient.
  • The AKI occurred subsequent to the use of sodium metamizole.

Findings:

  • Metamizole can induce kidney injury through various mechanisms.
  • This case underscores a potential nephrotoxic risk associated with metamizole.

Implications:

  • Emphasizing the risk of metamizole-induced kidney injury is crucial due to its widespread use.
  • Clinicians should consider metamizole as a potential cause of AKI in relevant patient populations.
  • Further research into metamizole's nephrotoxicity mechanisms is warranted.

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