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Multiple myeloma manifesting as an ocular salmon patch - a case report
Elad Ben Artsi1, Michael R Barkley1, Jwu J Khong1
1Orbital Plastic and Lacrimal Unit, Royal Victorian Eye and Ear Hospital , Melbourne, Australia.
Orbit (Amsterdam, Netherlands)
|November 15, 2019
Summary
Multiple myeloma, a rare cause of conjunctival salmon patches, can manifest in the eye. This case highlights the importance of considering multiple myeloma in the differential diagnosis of such ocular lesions.
Area of Science:
- Ophthalmology
- Hematology
- Oncology
Background:
- Multiple myeloma (MM) is a prevalent, incurable hematologic malignancy.
- Ocular surface manifestations of MM are rare but diverse.
- Conjunctival 'salmon patch' is a characteristic sign with differential diagnoses including lymphoma.
Observation:
- A 33-year-old female presented with a relapse of MM.
- The relapse manifested as a conjunctival 'salmon patch'.
- The patient responded well to medical management and autologous stem cell transplantation.
Findings:
- The conjunctival salmon patch was a manifestation of relapsed multiple myeloma.
- No surgical excision of the ocular lesion was required.
- Medical management and ASCT were effective.
Implications:
- Multiple myeloma should be included in the differential diagnosis of conjunctival salmon patches.
- This finding expands the understanding of MM's clinical ophthalmic manifestations.
- Early recognition can guide appropriate patient management.

