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Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
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Embolization using hydrogel-coated coils for pulmonary arteriovenous malformations.
T Iguchi1, T Hiraki1, Y Matsui1
1Department of Radiology, Okayama University Medical School, 2-5-1 Shikata-cho kita-ku, Okayama 700-8558, Japan.
Diagnostic and Interventional Imaging
|November 15, 2019
Summary
Embolization using hydrogel-coated coils effectively treated pulmonary arteriovenous malformations (PAVMs) with a 100% success rate in a 1-year follow-up. This safe and effective treatment option for PAVMs showed no recanalization or reperfusion.
Area of Science:
- Interventional Radiology
- Vascular Surgery
- Pulmonary Medicine
Background:
- Pulmonary arteriovenous malformations (PAVMs) are abnormal connections between pulmonary arteries and veins.
- Embolization is a primary treatment for PAVMs, aiming to prevent complications like hemorrhage or stroke.
- Evaluating novel embolic agents is crucial for improving treatment outcomes.
Purpose of the Study:
- To prospectively assess the safety and efficacy of embolization using hydrogel-coated coils for PAVM treatment.
- To determine the technical success and complication rates associated with this technique.
Main Methods:
- Prospective evaluation of 21 PAVMs in 19 patients treated with venous sac embolization (VSE) and feeding artery embolization.
- Mandatory use of hydrogel-coated coils (≥1) for VSE; additional bare platinum coils were used as needed.
- Pulmonary arteriography at 1 year to assess recanalization or reperfusion.
Main Results:
- Successful embolization in 20/21 PAVMs (95% technical success rate).
- Feeding artery embolization performed in 85% of successful cases.
- 100% success rate (19/19 PAVMs) with no recanalization or reperfusion at 1-year follow-up.
- One Grade 4 adverse event (coil migration) occurred but was managed without sequelae.
Conclusions:
- Venous sac embolization with hydrogel-coated coils and additional feeding artery embolization is a safe and effective treatment for PAVMs.
- Hydrogel-coated coils demonstrate favorable outcomes in PAVM embolization, with high technical success and long-term efficacy.
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