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Meningioma Mimicking Fibrous Dysplasia
Nur Afiah Kamaluddin1, Ahmad Hadif Zaidin Samsudin2, Wan-Hazabbah Wan Hitam1
1Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, MYS.
Abstract:
Despite being among the common primary intracranial tumors, intraosseous craniofacial meningioma is the least common subtype of meningioma accounting for only 1-2% of intracranial meningiomas. Interestingly, it can display clinical and radiologic features that can be confused for fibrous dysplasia. Scan imaging and biopsy are crucial for the diagnosis as well as for further proper treatment. We report a case of unilateral eye proptosis and optic neuropathy which was initially thought for fibrous dysplasia. Later the histopathology revealed meningioma grade 1. As the clinical presentations are almost undifferentiated, diagnosis and further prompt treatment are challenging.
Insights
Intraosseous craniofacial meningioma, a rare tumor, can mimic fibrous dysplasia on imaging. Prompt diagnosis via imaging and biopsy is crucial for effective treatment of this challenging condition.
Area of Science:
- Neuro-oncology
- Craniofacial Surgery
- Radiology
Background:
- Intraosseous craniofacial meningiomas are rare, accounting for 1-2% of intracranial meningiomas.
- These tumors can present with clinical and radiologic features mimicking other conditions, such as fibrous dysplasia.
Observation:
- A case presented with unilateral eye proptosis and optic neuropathy, initially misdiagnosed as fibrous dysplasia.
- Histopathology confirmed the diagnosis as a grade 1 meningioma.
Findings:
- The study highlights the diagnostic challenges posed by intraosseous craniofacial meningioma due to its non-specific presentation.
- Accurate diagnosis relies on a combination of advanced imaging techniques and histopathological examination.
Implications:
- Early and accurate diagnosis of intraosseous craniofacial meningioma is critical for timely intervention and improved patient outcomes.
- Distinguishing meningioma from fibrous dysplasia is essential for appropriate surgical and therapeutic planning.
