A Recurrent Case of Cryoglobulin-related Leukocytoclastic Vasculitis with an Unexpected Etiology

We report a 64-year-old man presenting with cutaneous leukocytoclastic vasculitis, the underlying etiology of which was established as hepatitis C infection with associated cryoglobulinemia. This pathophysiologic state presented clinically as recurrent cutaneous vasculitic eruptions with the absence of any other clinical manifestations except for mild ankle swelling and weakness. This case clearly relates the need to consider hepatitis C as a potential etiologic factor in all patients with cutaneous vasculitis, and we suggest that viral hepatitis screening should be done routinely in all patients presenting with cutaneous vasculitis.