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Updated: Jan 3, 2026

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
A unilateral dermatomal venous malformation
Elisabeth Smolle1, David Benjamin Lumenta2, Johannes Haybaeck3
1Division of Angiology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Abstract:
Venous malformations (VMs) are the most common vascular malformations, forming 44% to 64% of all vascular malformations. We report a case of a patient suffering from unilateral dermatomal VM. The VM was strictly confined to the right C6 dermatome. We propose that unilateral dermatomal VM is a prime example of somatic mosaicism in vascular development. Unilateral dermatomal VM seems to have a similar pathogenesis to the Sturge-Weber syndrome and may also be caused by somatic mutations disrupting the development of skin veins.
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