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Marfan's syndrome associated with Wolff-Parkinson-White syndrome type B
1Royal Postgraduate Medical School, Hammersmith Hospital, London, U.K.
Abstract:
A case of Marfan's syndrome associated with Wolff-Parkinson-White (WPW) syndrome is described and a discussion follows on the possible relationship of the two conditions. Isolated cases of such an association have been previously reported. It is possible that the association is more common than was previously recognized and the two conditions may share a common pathological basis. Moreover, WPW syndrome may contribute to the cardiac morbidity of Marfan's syndrome.
Insights
Marfan's syndrome and Wolff-Parkinson-White (WPW) syndrome may be more common than previously thought. This association might share a common cause and WPW syndrome could worsen cardiac issues in Marfan's syndrome.
Area of Science:
- Cardiology
- Genetics
Background:
- Marfan syndrome is a genetic disorder affecting connective tissue.
- Wolff-Parkinson-White (WPW) syndrome is a cardiac condition characterized by extra electrical pathways.
Observation:
- A case report details an association between Marfan syndrome and WPW syndrome.
- Previous isolated reports suggest this comorbidity.
Findings:
- The co-occurrence of Marfan syndrome and WPW syndrome may be underestimated.
- A shared underlying pathological basis for both conditions is hypothesized.
Implications:
- WPW syndrome might exacerbate cardiac morbidity in patients with Marfan syndrome.
- Further research is warranted to explore the connection and its clinical significance.
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