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Updated: Jan 3, 2026
Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty
Published on: September 17, 2014
Descemet Stripping Only for a Chronic Descemet Detachment After Cataract Surgery
Kristin E Hirabayashi1, David Mark2, Jackson Lau2
1Byers Eye Institute, Stanford University, Palo Alto, CA; and.
Purpose:
To describe a case of postsurgical corneal decompensation in a patient with Fuchs endothelial dystrophy with a sectoral Descemet detachment and corneal edema that was successfully managed with a targeted Descemet stripping only (DSO) procedure.
Methods:
This is a case report and review of the literature.
Results:
A female patient with Fuchs endothelial dystrophy presented with a 6-month history of a persistent sectoral Descemet membrane detachment after cataract surgery with overlying corneal edema. Specular microscopy demonstrated moderate cell dropout with a cell density of 929 cells/mm in the affected eye. Intracameral air injection was attempted without improvement, and a sectoral DSO procedure was performed. Netarsudil and prednisolone were used postoperatively, and she demonstrated gradual improvement with resolution of the edema by postoperative week 10 and a central endothelial cell density of 675 cells/mm by postoperative month 8.
Conclusions:
DSO is a viable therapy in certain cases of postsurgical corneal decompensation.
