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Updated: Jan 3, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Association of diet and headache
Soodeh Razeghi Jahromi1,2, Zeinab Ghorbani3, Paolo Martelletti4
1Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Dietary interventions like ketogenic and low-glycemic diets show promise for migraine relief. Balancing omega-3 and omega-6 fatty acids and weight loss also aid migraine prevention.
Area of Science:
- Neurology
- Nutritional Science
- Integrative Health
Background:
- Migraine is a leading cause of disability worldwide, affecting 14.4% of the global population.
- Pathophysiological mechanisms include vascular dysfunction, cortical spreading depression, trigeminovascular pathway activation, and inflammation.
- Integrative health approaches, particularly dietary interventions, are gaining interest for migraine management.
Purpose of the Study:
- To review the available evidence on the effects of dietary interventions on headache and migraine.
- To explore how various diets may influence migraine pathophysiology and provide prophylaxis.
Main Methods:
- A comprehensive literature search was conducted on PubMed/MEDLINE and ScienceDirect.
- Included publications focused on headache/migraine and dietary interventions up to May 2019.
Main Results:
- Ketogenic and modified Atkins diets may offer neuroprotection, improve mitochondrial function, and reduce inflammation and CGRP levels.
- Low glycemic diets may attenuate inflammation, while weight loss diets can help manage obesity-related headaches.
- Balancing omega-3 and omega-6 fatty acids and targeted elimination diets for food sensitivities show potential benefits.
Conclusions:
- Dietary strategies such as ketogenic, low-glycemic, and weight loss diets are promising for migraine prophylaxis.
- Modulating fatty acid intake and using elimination diets for identified sensitivities can also be effective.
- Further research is needed to fully elucidate the role of diet in migraine management.
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