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Outcomes of colonic resection for chronic idiopathic constipation in childhood
1The Great North Children's Hospital, Newcastle upon Tyne, UK.
Insights
Colonic resection for severe constipation in children offers a chance for improved bowel function, but carries a significant risk of requiring a permanent stoma. Outcomes varied, with no single surgical approach proving superior.
Area of Science:
- Pediatric surgery
- Gastroenterology
- Colorectal surgery
Background:
- Severe constipation in children can be refractory to medical management.
- Surgical intervention, including colonic resection, is considered for select cases.
- Different surgical techniques exist, each with potential outcomes and complications.
Purpose of the Study:
- To evaluate the outcomes of various colonic resection procedures for intractable constipation in pediatric patients.
- To compare the effectiveness of pan-proctocolectomy with ileoanal pouch anastomosis (IPAA), total colectomy with ileorectal anastomosis (IR), and segmental resections (SR).
Main Methods:
- Prospective data collection of colonic resections performed over 20 years.
- Classification of outcomes as Good (anal defecation, no soiling), Intermediate (anal defecation with soiling or need for antegrade continence enema [ACE]), or Poor (permanent stoma).
- Recording of all complications associated with each procedure.
Main Results:
- 22 children underwent colonic resection; mean follow-up was 40 months.
- Outcomes were: Good in 45%, Intermediate in 18%, and Poor (permanent stoma) in 36%.
- Surgical resection restored anal defecation in 75% of children who previously had a stoma; no procedure demonstrated superior outcomes or complication rates.
Conclusions:
- Colonic resection may be a viable option for carefully selected pediatric patients with severe constipation.
- Parents must be counseled regarding the substantial risk (approximately 40%) of requiring a permanent stoma post-surgery.
- The choice of resection technique did not significantly influence the overall success or complication profile.
Aims:
The purpose of this study was to describe the outcomes of colonic resection for constipation in children. Three different types of resection are compared: pan-proctocolectomy with ileoanal pouch anastomosis (IPAA), total colectomy with ileorectal anastomosis (IR), and segmental resections and anastomosis (SR).
Patients And Methods:
All colonic resections were prospectively recorded and their outcomes tabulated. Outcomes were classified as Good: anal defecation with no soiling; Intermediate: anal defecation with occasional soiling or need for ACE; Poor: a permanent stoma. All complications were also recorded.
Results:
22 children underwent colonic resection over a 20 year period. Mean follow up was 40 months. 18 had prior antegrade continent enema (ACE), and 12 had a prior stoma. 13 underwent IPAA, 6 IR, and 3 SR. 10 (45%) had a good outcome, 4 (18%) had an intermediate outcome, and 8 (36%) had a poor outcome. Resection restored 9/12 (75%) of children with a preexisting stoma to anal defecation. No procedure produced better outcome than the others in terms of results or complications.
Conclusions:
There may be a role for colonic resection in selected constipated children, but parents should be warned that there remains a significant possibility of a permanent stoma. Our study suggests that around two-fifths will be left with a permanent stoma.
Level Of Evidence:
Level IV.
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