Outcomes of colonic resection for chronic idiopathic constipation in childhood

Ryo Tamura1, Bruce Jaffray1

  • 1The Great North Children's Hospital, Newcastle upon Tyne, UK.

Insights

Colonic resection for severe constipation in children offers a chance for improved bowel function, but carries a significant risk of requiring a permanent stoma. Outcomes varied, with no single surgical approach proving superior.

Area of Science:

  • Pediatric surgery
  • Gastroenterology
  • Colorectal surgery

Background:

  • Severe constipation in children can be refractory to medical management.
  • Surgical intervention, including colonic resection, is considered for select cases.
  • Different surgical techniques exist, each with potential outcomes and complications.

Purpose of the Study:

  • To evaluate the outcomes of various colonic resection procedures for intractable constipation in pediatric patients.
  • To compare the effectiveness of pan-proctocolectomy with ileoanal pouch anastomosis (IPAA), total colectomy with ileorectal anastomosis (IR), and segmental resections (SR).

Main Methods:

  • Prospective data collection of colonic resections performed over 20 years.
  • Classification of outcomes as Good (anal defecation, no soiling), Intermediate (anal defecation with soiling or need for antegrade continence enema [ACE]), or Poor (permanent stoma).
  • Recording of all complications associated with each procedure.

Main Results:

  • 22 children underwent colonic resection; mean follow-up was 40 months.
  • Outcomes were: Good in 45%, Intermediate in 18%, and Poor (permanent stoma) in 36%.
  • Surgical resection restored anal defecation in 75% of children who previously had a stoma; no procedure demonstrated superior outcomes or complication rates.

Conclusions:

  • Colonic resection may be a viable option for carefully selected pediatric patients with severe constipation.
  • Parents must be counseled regarding the substantial risk (approximately 40%) of requiring a permanent stoma post-surgery.
  • The choice of resection technique did not significantly influence the overall success or complication profile.
Abstract

Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
411
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
648
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
706
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
998
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
474
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
688