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Related Concept Videos

Autoimmune Disorders

Autoimmune Disorders

Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...

Special Features of Adaptive Immunity

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The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...

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Related Experiment Video

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Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity

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Published on: April 11, 2019

Autoimmunity: An in-sight narrative.

Girija Venkatesh¹

¹Independent Author and Educationist, Harinivas, KHB Colony, Koramangala 5th Block, Bengaluru 560 095 INDIA.

Indian Journal of Medical Ethics

|November 16, 2019

Summary

This summary is machine-generated.

Autoimmune conditions involve more than just inflammation, impacting lifestyle, mental, and emotional well-being. Understanding these interconnected factors is key to managing autoimmune dis-ease.

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Area of Science:

Integrative immunology
Mind-body medicine
Autoimmune disease research

Background:

Autoimmune conditions are characterized by the immune system attacking self-antigens, blurring self/non-self boundaries.
Conventional medicine primarily focuses on the immune system's inflammatory response.
A holistic view is needed to understand the multifaceted nature of autoimmune dis-ease.

Observation:

The author's personal journey with autoimmunity revealed connections beyond the immune system.
Lifestyle factors, including diet and environment, play a significant role.
Mental and emotional states demonstrably influence the experience and progression of autoimmune conditions.

Findings:

Autoimmune dis-ease is influenced by a complex interplay of biological, psychological, and social factors.
The boundary between self and non-self is not solely an immunological concept but also influenced by holistic health.
Integrating lifestyle, mental, and emotional perspectives offers a more comprehensive understanding of autoimmunity.

Implications:

This holistic perspective can inform more personalized and effective autoimmune disease management strategies.
Encourages a paradigm shift in understanding autoimmune conditions beyond a purely biomedical model.
Highlights the importance of patient-centered, integrative approaches in autoimmune care.