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Visualization of Bacterial Resistance using Fluorescent Antibiotic Probes
Published on: March 2, 2020
Optically-controlled supramolecular self-assembly of an antibiotic for antibacterial regulation
Xuancheng Fu1, Haotian Bai, Ruilian Qi
1Beijing National Laboratory for Molecular Sciences, Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China. wangshu@iccas.ac.cn liulibing@iccas.ac.cn.
Abstract:
We report a supramolecular photo-responsive antibiotic (azobenzene-norfloxacin/αCD). This supramolecule exhibited a higher "on-off" ratio of antibacterial ability than azobenzene-norfloxacin alone under UV irradiation. It offers an approach to efficiently regulate the activity of antibiotics by combining the supramolecular and light-regulating strategies together.
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