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Prognostic role of Mini-Mental State Pediatric Examination (MMSPE) on neuropsychological functioning
Elisa Cainelli1,2, Deborah Lidia Di Giacomo3, Giulia Mantegazza4
1Department of Developmental Psychology and Socialization, University of Padova, Via Venezia 8, 35133, Padua, Italy. cainelli.elisa@gmail.com.
Insights
The Mini-Mental State Pediatric Examinations (MMSPE) effectively identify neuropsychological impairments in children with neurological diseases. This tool aids in early detection and improves clinical practice for high-risk pediatric patients.
Area of Science:
- Pediatric Neurology
- Neuropsychology
Background:
- Neuropsychological impairments are common in children with neurological diseases.
- Early identification is crucial for effective intervention and management.
Purpose of the Study:
- To evaluate the diagnostic accuracy of the Mini-Mental State Pediatric Examinations (MMSPE) in identifying neuropsychological impairments.
- To assess the prognostic ability of MMSPE in pediatric neurological conditions.
Main Methods:
- MMSPE was administered to 60 children with neurological diseases.
- Children also underwent a comprehensive neuropsychological evaluation.
- Diagnostic performance metrics including accuracy, PPV, and NPV were calculated.
Main Results:
- MMSPE demonstrated good overall accuracy (0.83) and high specificity (0.91).
- The test showed strong negative predictive value (0.81) and positive predictive value (0.87).
- A significant odds ratio of 28.5 (p < 0.001) indicated strong predictive power.
Conclusions:
- MMSPE is a valuable tool for predicting neuropsychological problems in pediatric neurological diseases.
- The instrument can significantly enhance clinical practice by identifying children at high risk.
- This aids in timely and targeted interventions for affected children.
Objective:
The aim of this study was to evaluate the ability of the Mini-Mental State Pediatric Examinations (MMSPE) in the individuation of neuropsychological impairments.
Method:
MMSPE was administered to 60 children attending a primary or lower secondary school suffering from neurological diseases, admitted to our neuropsychology services. All children performed both a MMSPE examination and a neuropsychological evaluation. Results of neuropsychological evaluation and MMSPE were dichotomized. Positive predictive value (PPV), negative predictive value (NPV), and accuracy were also calculated.
Results:
The diagnostic performance of MMSPE showed a good overall accuracy (0.83, CI 95% 0.64-0.91), NPV (0.81, CI 95% 0.73-1.00), PPV (0.87, CI 95% 0.68-0.94), specificity (0.91, CI 95% 0.81-1.00), sensitivity (0.74, CI 95% 0.57-0.90), and odds ratio of 28.5 (CI 95% 6.6-123), p < 0.001.
Conclusions:
MMSPE has a good prognostic ability in predicting neuropsychological problems in the context of different neurological pediatric diseases. We suggest that this instrument could greatly improve pediatric clinical practice in identifying high-risk children.
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