Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

5.8K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.8K
Accuracy and Precision01:52

Accuracy and Precision

13.8K
Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value.  Highly accurate...
13.8K
Uncertainty in Measurement: Accuracy and Precision03:37

Uncertainty in Measurement: Accuracy and Precision

99.2K
Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value. 
99.2K
Sensitivity, Specificity, and Predicted Value01:13

Sensitivity, Specificity, and Predicted Value

1.2K
In healthcare diagnostics, laboratory tests play a crucial role in identifying and diagnosing a wide range of medical conditions. However, interpreting test results is not always straightforward. An abnormal test result does not always confirm the presence of a disease, just as a normal result does not guarantee its absence. To assess the reliability of these diagnostic tools, healthcare practitioners rely on two key statistical indicators: sensitivity and specificity.
Sensitivity is the...
1.2K
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

893
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
893

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Encapsulation enhances stromal cell survival for safe neonatal therapy: a pilot study.

World journal of pediatric surgery·2026
Same author

Acute Hyponatremia as a Telling Complication of Necrotizing Pancreatitis and Perforated Cholecystitis After Percutaneous Cholecystostomy.

ACG case reports journal·2026
Same author

Inducible lipid storage and steatosis in the human choroid plexus associated with age and adiposity.

bioRxiv : the preprint server for biology·2026
Same author

Detecting ctDNA Using Personalized Structural Variants to Forecast Recurrence in Localized Soft Tissue Sarcoma.

Clinical cancer research : an official journal of the American Association for Cancer Research·2026
Same author

A comparison of cancer treatment protocols in Australia, Canada, and the United Kingdom.

BMC cancer·2026
Same author

Thread- reinforced encapsulation devices (THRED) for therapeutic stem cell delivery.

Journal of pediatric surgery·2026

Related Experiment Video

Updated: Jan 3, 2026

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
13:24

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

Published on: April 11, 2016

12.2K

Qualifying and quantifying the precision medicine rhetoric.

Jasmine Lee1, Dina Hamideh2, Camille Nebeker3

  • 1Case Western Reserve University, Cleveland, OH, 44106, USA.

BMC Genomics
|November 16, 2019
PubMed
Summary

Global precision medicine initiatives often focus solely on biospecimens, limiting comprehensive genetic, lifestyle, and environmental data integration. Future efforts should incorporate multidimensional data for a holistic healthcare approach.

Keywords:
Big DataEvidence-based medicineGenomic medicineIndividualized medicineP4 medicinePersonalized medicinePrecision medicineStratified medicineTranslational medicine

More Related Videos

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

15.9K
Predictive Immune Modeling of Solid Tumors
08:50

Predictive Immune Modeling of Solid Tumors

Published on: February 25, 2020

7.4K

Related Experiment Videos

Last Updated: Jan 3, 2026

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
13:24

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

Published on: April 11, 2016

12.2K
Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

15.9K
Predictive Immune Modeling of Solid Tumors
08:50

Predictive Immune Modeling of Solid Tumors

Published on: February 25, 2020

7.4K

Area of Science:

  • Genomics and Bioinformatics
  • Translational Medicine
  • Public Health Initiatives

Background:

  • The global rise of precision medicine necessitates a comprehensive understanding of current research landscapes.
  • Existing precision medicine efforts were examined to map their scope and methodologies.
  • Analysis focused on terminology, geographic distribution, data types, and funding models.

Purpose of the Study:

  • To describe and map the emerging global precision medicine landscape.
  • To analyze the terminology and data types used in precision medicine initiatives.
  • To identify funding sources and geographic concentrations of precision medicine research.

Main Methods:

  • A targeted Google search was conducted using "precision medicine" and related terms.
  • Web pages were reviewed for geographic location, data types, program aims, sample size, and duration.
  • Descriptive statistics and qualitative content analysis were applied to collected data.

Main Results:

  • 84% of 108 identified programs collected only biospecimens, with 42% of multi-data programs including EHR and biospecimens.
  • 54% of programs collected two or more data types, potentially limiting understanding of genetic, lifestyle, and environmental interactions.
  • Most initiatives were government-funded (over 50%), concentrated in the US, Europe, and Asia.

Conclusions:

  • This study provides the first global map and qualification of the precision medicine landscape.
  • Precision medicine efforts vary widely, from large cohort studies to biorepositories.
  • Recommendations include incorporating multidimensional data for a holistic approach to precision medicine.