Cingulate cortex in pre-MCI cognition
Nathalie Sambuchi1, Yonas Endale Geda2, Bernard François Michel1
1Neurogeriatric Department, Sainte Marguerite Hospital, Marseille, France.
Abstract:
Studies of Alzheimer's disease over the years have focused on the prodromal stage, or mild cognitive impairment (MCI), in order to understand its evolution and to diagnose this pathology early. More recently, research has focused on an even earlier stage (pre-MCI) characterized in particular by a cognitive complaint. The purpose of this chapter is, first, to describe the different concepts defining pre-MCI, which refers to cognitive or memory complaint, and to define this concept based on biologic markers (abnormal proteins and neuroimaging). In the second part of the chapter, we describe the cognitive performance of these subjects (pre-MCI), and, finally, in the third part we describe the correlations linking cognitive performance of pre-MCI subjects to cingulate cortex, cingulate gyrus, and cingulum bundle.
More Related Videos
08:43Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment
Published on: August 7, 2017
06:50A Preclinical Controlled Cortical Impact Model for Traumatic Hemorrhage Contusion and Neuroinflammation
Published on: June 10, 2020
Related Concept Videos
Role of Cerebellum and Prefrontal Cortex in Memory
Motor and Sensory Areas of the Cortex
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
Somatosensory, Motor, and Association Cortex
Association Areas of the Cortex
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Lobes of the Cerebrum
Frontal lobe
The frontal lobes, located behind the forehead, are the command center of our brain, controlling personality, intelligence, and voluntary muscle movements....
Role of Hippocampus in Memory
