Cingulate seizures and recent treatment strategies
Katherine Inoyama1, Orrin Devinsky1
1Department of Neurology, New York University School of Medicine, New York, NY, United States.
Handbook of Clinical Neurology
|November 17, 2019
Summary
Cingulate epilepsy presents diverse symptoms, making diagnosis challenging. Advanced imaging and novel treatments like laser ablation offer improved localization and therapeutic options.
Area of Science:
- Neurology
- Epileptology
- Neuroimaging
Background:
- Cingulate epilepsy exhibits varied semiology and seizure types.
- Identifying the seizure onset zone is diagnostically challenging, especially without imaging lesions.
- Electroencephalogram findings are often poorly localized.
Purpose of the Study:
- To review the clinical features, diagnostic challenges, and treatment modalities for cingulate epilepsy.
- To highlight the role of advanced neuroimaging in localizing seizure activity.
- To discuss emerging therapeutic strategies beyond conventional treatments.
Main Methods:
- Review of clinical features and semiologic manifestations.
- Analysis of electroencephalogram findings in cingulate epilepsy.
- Evaluation of multimodal imaging techniques for ictal localization.
- Summary of current and novel treatment options.
Main Results:
- Clinical features can indicate specific cingulate gyrus subregion involvement.
- Multimodal imaging shows promise for improving ictal localization.
- Novel treatments offer alternatives for refractory cases.
Conclusions:
- Cingulate epilepsy diagnosis requires careful clinical and electrophysiologic assessment.
- Advanced imaging techniques are crucial for precise localization.
- Emerging therapies expand treatment possibilities for cingulate epilepsy management.
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