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Risk Factors for Red Blood Cell Transfusions in Children Undergoing Cardiac Catheterization

R Allen Ligon1, Laura A Downey1, David L Gruenewald1

  • 1Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA.

The Journal of Pediatrics
|November 17, 2019
PubMed

Insights

Infants with complex heart conditions undergoing cardiac catheterization face a higher risk of red blood cell transfusions. Factors like procedure length and blood loss increase this risk, guiding clinical decisions.

Area of Science:

  • Pediatric Cardiology
  • Transfusion Medicine

Background:

  • Pediatric cardiac catheterization is a common procedure.
  • Red blood cell transfusions (RBCTs) are sometimes necessary post-procedure.
  • Identifying risk factors for RBCTs can optimize patient care.

Purpose of the Study:

  • To identify risk factors for red blood cell transfusions (RBCTs) after pediatric cardiac catheterization.
  • To analyze patient and procedural variables associated with RBCTs.

Main Methods:

  • Retrospective review of pediatric cardiac catheterizations from 2012-2017.
  • Primary endpoint: RBCT within 72 hours of catheterization.
  • Generalized linear modeling to assess risk factors.

Main Results:

  • 13.8% of 6028 procedures resulted in RBCTs.
  • Infants had the highest RBCT incidence (37.6%).
  • Risk factors included younger weight, complex 2-ventricle/single ventricle anatomy, intensive care unit stay, longer procedure duration, and lower oxygen saturation.

Conclusions:

  • Infants with complex congenital heart disease are at the highest risk for RBCTs.
  • Procedure length, blood loss, and oxygen saturation are significant risk factors.
  • Consideration of these factors is crucial for planning pediatric cardiac catheterizations to minimize RBCTs.
Abstract

Keywords:
cath labpediatric cardiology

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