Chronic, Gross Hematuria Caused by Idiopathic Ureteric Stricture

Robert L Myette1, Amy Acker2

  • 1Department of Pediatrics, Queen's University at Kingston Health Science Centre, Kingston, Ontario, Canada robert.myette@queensu.ca.

Pediatrics
|November 17, 2019
PubMed

Insights

A 10-year-old boy experienced 5 years of chronic hematuria (blood in urine), leading to anemia and distress. An idiopathic ureteric stricture was diagnosed and treated with stenting, resolving the hematuria and improving his well-being.

Area of Science:

  • Pediatric Urology
  • Nephrology
  • Medical Diagnostics

Background:

  • Chronic gross hematuria in children can be challenging to diagnose.
  • Prolonged diagnostic workups can cause significant psychosocial distress.
  • Differential diagnoses included nutcracker phenomenon.

Observation:

  • A 10-year-old boy presented with 5 years of daily gross hematuria.
  • Extensive workup, including renal biopsy, was inconclusive.
  • Severe iron deficiency anemia and psychosocial distress were noted.

Findings:

  • Idiopathic unilateral ureteric stricture was identified upon closer ureteral inspection.
  • Eight weeks of ureteral stenting led to complete resolution of hematuria.

Implications:

  • Ureteric strictures should be considered in the differential diagnosis of chronic pediatric hematuria.
  • Timely diagnosis and treatment of urological conditions can alleviate patient distress.
  • Successful stenting offers a minimally invasive treatment option for ureteric strictures.

Related Concept Videos

Renal Corpuscle01:20

Renal Corpuscle

The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
6.7K
Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
802
Ureters01:22

Ureters

The ureters are retroperitoneal tubes located on either side of the vertebral column. They are responsible for transporting urine from each kidney to the urinary bladder. These tubes have thick walls and are approximately 25-30 cm long. Their diameter is around 10 mm at the renal pelvis, gradually narrowing to 1 mm as the ureter obliquely enters the posterior bladder wall through the ureteric orifices. The shape of these orifices is slit-like, which helps to prevent urine backflow toward the...
1.3K
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
523
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
337
Disorders of the Urinary System01:20

Disorders of the Urinary System

The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
1.0K