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Updated: Jan 3, 2026

Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry
Published on: October 18, 2019
Enamine/Transition Metal Combined Catalysis: Catalytic Transformations Involving Organometallic Electrophilic
Samson Afewerki1, Armando Córdova2
1Department of Natural Sciences, Mid Sweden University, 851 70, Sundsvall, Sweden. samson.afewerki20@gmail.com.
Abstract:
The concept of merging enamine activation catalysis with transition metal catalysis is an important strategy, which allows for selective chemical transformations not accessible without this combination. The amine catalyst activates the carbonyl compounds through the formation of a reactive nucleophilic enamine intermediate and, in parallel, the transition metal activates a wide range of functionalities such as allylic substrates through the formation of reactive electrophilic π-allyl-metal complex. Since the first report of this strategy in 2006, considerable effort has been devoted to the successful advancement of this technology. In this chapter, these findings are highlighted and discussed.
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