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Physiologic and anatomic basis for contralateral R1 in blink reflex.

B Soliven¹, J Meer, A Uncini

¹Department of Neurology, Columbia-Presbyterian Medical Center, New York, NY.

|August 1, 1988

Summary

Researchers investigated contralateral R1 responses in healthy individuals. Findings suggest crossed trigeminofacial pathways may exist, with peripheral trigeminal nerve stimulation also potentially causing these responses.

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Area of Science:

Neuroscience
Ophthalmology

Background:

Contralateral R1 responses are observed in certain neurological conditions.
The exact mechanism and origin of these responses in healthy subjects are not fully understood.

Purpose of the Study:

To investigate the appearance rate and mechanism of contralateral R1 responses in normal subjects.
To determine the pathways involved in generating these responses.

Main Methods:

Facilitating maneuvers including orbicularis oculi contraction and median nerve conditioning stimulus were employed.
Stimulating anode position was altered, and contralateral supraorbital nerve was blocked to assess response origin.

Main Results:

Contralateral R1 responses were elicited using specific facilitating maneuvers.

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Responses were confirmed to be of peripheral origin through nerve blockade, indicating stimulation of peripheral trigeminal ophthalmic sensory fibers.

Conclusions:

Crossed trigeminofacial pathways likely exist in normal subjects.
Contralateral R1 responses can arise from peripheral trigeminal nerve stimulation in some cases.