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Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
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Dosage Regimen: Individualization01:24

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Individualization in dosing regimens is the customization of medication doses for individual patients. Its necessity arises from the goal of maximizing therapeutic benefits while minimizing risks. This approach is pivotal because human responses to drugs can vary widely; what is effective for one person may be inadequate or excessive for another. Interpatient (intersubject) variability refers to differences in drug responses between individuals, while intrapatient (intrasubject) variability...
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It is not uncommon for complete drug pharmacokinetic profiles to remain elusive in pharmacokinetics. This necessitates certain educated assumptions by pharmacokineticists to determine appropriate dosage regimens without comprehensive pharmacokinetic data from animal or human studies. One prevalent assumption is setting the bioavailability factor, denoted as F, to 1 or 100%. This assumption caters to the scenario where a drug doesn't achieve full systemic absorption, resulting in the patient...
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Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
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Drug Control Governance: Regulatory Bodies and Their Impact01:03

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Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...
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Community pharmacist-led medication review procedures across Europe: Characterization, implementation and

Tamara Leila Imfeld-Isenegger1, Inês Branco Soares2, Urska Nabergoj Makovec3

  • 1Pharmaceutical Care Research Group, University of Basel, Switzerland.

Research in Social & Administrative Pharmacy : RSAP
|November 18, 2019
PubMed
Summary

Community pharmacies across Europe show varied implementation of medication reviews, with simpler types like Type 1 and 2a being more common. Ongoing projects suggest future growth in these essential patient care services.

Keywords:
Community pharmacy servicesEuropeMedication reviewPrimary health careRemunerationService implementation

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Area of Science:

  • Pharmacy Practice
  • Health Services Research
  • Medication Management

Background:

  • The Pharmaceutical Care Network Europe (PCNE) established a classification system for medication reviews in 2016.
  • A gap exists in understanding the implementation and reimbursement of these medication review procedures across European community pharmacies.

Purpose of the Study:

  • To describe the types of medication review procedures implemented in European community pharmacies.
  • To assess the level of implementation and third-party remuneration for medication reviews across Europe.

Main Methods:

  • An online survey was distributed to experts in 44 European countries.
  • The survey characterized medication review procedures based on the PCNE classification, implementation status, and remuneration.
  • Data triangulation and consensus-seeking were employed to ensure data reliability.

Main Results:

  • Data from 34 countries (77% response rate) revealed that 55.9% offered at least one type of medication review.
  • Type 1 (medication history) and Type 2a (history + patient interview) reviews were most prevalent.
  • Only ten services/projects reported third-party remuneration, highlighting significant heterogeneity.

Conclusions:

  • There is substantial variation in medication review procedures, implementation, and remuneration across Europe.
  • Type 1 and 2a medication reviews are more feasible for community pharmacy implementation compared to Type 2b and 3.
  • The number of ongoing medication review projects indicates potential for future service expansion.