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Updated: Jan 3, 2026
Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
Published on: September 14, 2018
Ingestible sensors correlate closely with peripheral temperature measurements in febrile patients
Fanyu Huang1, Chloe Magnin1, Philippe Brouqui1
1Department of Research Microbes Evolution Phylogeny and Infections (MEPHI), The Institute for Development Research (IRD), University Hospital Institute-Mediterranean infection, Aix Marseille University, 19-21 Boulevard Jean MOULIN, 13005 Marseille, France.
Backgrounds:
Reliable non-invasive methods for measuring body temperature are essential for the diagnosis and monitoring of infectious disease.
Methods:
This study used Intraclass Correlation Coefficients (ICC) and the Bland- Altman plot to analyse the agreement between temperature measurements using an ingestible capsule sensor, a skin sensor and two non-invasive peripheral temperature measurements (axillary and infrared non-contact), collected from a population of febrile patient admitted for infectious disease.
Results:
Of the 77 febrile patients screened, 26 patients were enrolled. The ICC between axillary temperature measurements (Taxi) vs. non-contact measurements (Tno-c) were 0.34 [-0.18; 0.63], 0.87 [0.55; 0.94] between Taxi vs. ingestible capsule measurements (Tcap) and 0.12 [-0.09; 0.37] between Taxi vs. Tetac. The mean difference between Taxi vs Tno-c was -1.18 °C with limits of agreement (LoA) from -2.96 to 0.58 °C. The mean difference between Taxi vs Tcap was 0.48 °C, with LoA from -0.60 to 1.56 °C. The mean difference between Taxi vs Tetac was -4.23 °C with LoA from -7.22 to -1.23 °C.
Conclusions:
Ingestible capsule measurements are reliable enough to adequately estimate the core body temperature in clinical practice. Its non-invasiveness, and the real-time remote control offer new opportunities for future research into fever during infectious diseases.
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