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Horst Otto Stoeckel: Clinician, Administrator, Researcher
1Kasumi Arakawa Professor of Anesthesiology, University of Kansas Medical Center, Kansas City, KS, USA.
Journal of Anesthesia History
|November 19, 2019
Summary
Horst Otto Stoeckel pioneered quantitative clinical pharmacology in anesthesia, developing algorithms for automatic dosing control. His work laid the foundation for target-controlled infusion systems in anesthesia.
Area of Science:
- Anesthesiology
- Clinical Pharmacology
- Medical Informatics
Background:
- Horst Otto Stoeckel's early life and education in Germany.
- His foundational training in surgery, internal medicine, and anesthesiology.
- Stoeckel's escape from East Berlin and subsequent career in West Germany.
Discussion:
- Stoeckel's leadership as Chair of Anesthesiology at the University of Bonn.
- His development of patient care, teaching, and research programs.
- Establishment of a long-term research program in quantitative clinical pharmacology and anesthesia modeling.
Key Insights:
- Development of basic algorithms for automatic dosing control using closed-loop feedback systems.
- Foundational contribution to target-controlled infusion (TCI) of intravenous and inhalation anesthetics.
- Interdisciplinary research approach involving biochemistry, physics, and analytical methods.
Outlook:
- The lasting impact of Stoeckel's research on modern anesthesia practices.
- His transition to a second career as a collector and museum founder.
- The significance of his contributions to the field of quantitative modeling and control in anesthesia.